Tristana matchup: You are at a disadvantage for the same reasons as in the Lucian matchup, but this opponent should be somewhat easier to handle. You have a chance to win once your ultimate is available, but be careful of Tristana countering with her own R or dodging with her W.

Karma matchup: She relentlessly bullies Neeko, making the laning phase up to level 6 extremely tough. Things might get a bit easier if you can block Karma's RQ with Neeko's W. Once you unlock your ultimate, however, you can win the matchup.

Janna matchup: The early game isn't an overly difficult matchup, but Janna can easily counter Neeko's ultimate with her own ultimate and Q. I recommend purchasing Verdant Barrier after completing your first item.

Nami matchup: Since Nami cannot cast her W on Neeko while she is in minion form, you can secure a favorable trade by immediately shapeshifting after harassing with your Q.

Zyra matchup: By transforming into a melee champion, you can destroy Zyra's plants with a single auto-attack. Additionally, if you activate Neeko's W just as a plant is about to bloom, you can make the W absorb the attack.

Yuumi matchup: If you are about to get hit by Yuumi's Q, you can prevent her from healing by transforming into a minion. You can also block it with your W, but if you are in champion form, she will heal.

Elise matchup: Harass Elise. Block her E with your W. Watch out for her E-Flash.

Alistar matchup: Buy Verdant Barrier so Alistar doesn't knock away your ultimate with his W.

Maokai matchup: You can absorb Maokai's E with your minion form to take almost no damage, or simply clear it with your W. Make sure to save your W to counter Maokai's R. Verdant Barrier is also a recommended item; since your clone inherits the Verdant Barrier effect (independent of the main body's cooldown), you can effectively block Maokai's R.

Milio matchup: Start by buying Heal Cut so you can win an all-in at level 6. Also, it’s fun to get sent flying by Milio’s Q while disguised as a minion.

Shaco matchup: Purchase an Oracle Lens to prevent him from going all-in or escaping.

Blitzcrank matchup: Just use "W" to block his grab. There's nothing difficult about it.

Pyke matchup: Just use "W" to block his grab. There's nothing difficult about it.

Soraka matchup: Even if you are about to get hit by Soraka's Q, you can completely shut her down by mimicking a minion, preventing her from gaining any buffs whatsoever.

Thresh matchup: Just use "W" to block his grab. There's nothing difficult about it.

Leona matchup: You can dodge Leona's E by shapeshifting into a minion. You can also avoid her Q's stun by turning invisible with Neeko's W right before it hits—though the timing is quite tight.

Nautilus matchup: Just use "W" to block his grab. There's nothing difficult about it.

Camille matchup: You can dodge Camille's E by transforming into a minion. You can also block it with Neeko's W.

Shen matchup: You can dodge Shen's E by transforming into a minion.