Kai'Sa vs Vayne Learn how to vs Vayne as Kai'Sa. We aggregate Kai'Sa vs Vayne high elo matchup stats from Kai'Sa one tricks and mains Build RankingCountersARAMStreamersBETARole:vs. BestWorstBest Bot Picks vs Kai'Sa BotBest Lane Matchups vs Kai'Sa Bot Kai'Sa Mains vs Vayne Bot vs VayneOverall Stat 53.8%54.9%Win Rate2.77:12.88:1KDA31 CS Diff pre 693 CS Diff at 15199 CS Diff9447 Gold Diff pre 6425142 Gold Diff at 15982790 Gold Diff50-13 EXP Diff pre 626783 EXP Diff at 15609518 EXP DiffAverage Stats over TimeGold DiffCS DiffEXP DiffNumber of games: 500 *Onetricks tend to have better-than-average stats due to their champion masteryKai'Sa OTP Builds vs Vayne Bot